ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate

ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate - Names and Identifiers

Name	ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate
Synonyms	ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate 5-pyrimidinecarboxylic acid, 2-(trifluoromethyl)-, ethyl ester
CAS	304693-64-9
InChI	InChI=1/C8H7F3N2O2/c1-2-15-6(14)5-3-12-7(13-4-5)8(9,10)11/h3-4H,2H2,1H3

ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate - Physico-chemical Properties

Molecular Formula	C8H7F3N2O2
Molar Mass	220.1485896
Density	1.344g/cm³
Boling Point	194.365°C at 760 mmHg
Flash Point	71.349°C
Vapor Presure	0.443mmHg at 25°C
Storage Condition	2-8℃
Refractive Index	1.448

ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate - Introduction

ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate is an organic compound with the chemical formula C8H6F3NO2. The following is an introduction to some of its properties, uses, formulation and safety information:

Nature:
-Appearance: colorless liquid
-Melting point:-23 ℃
-Boiling point: 146-148 ℃
-Density: 1.420 g/mL
-Solubility: Soluble in organic solvents such as ethanol, ether and dichloromethane

Use:
- ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate is widely used in pesticide and pharmaceutical fields.
-In the field of pesticides, it is usually used as an intermediate for herbicides and used to prepare other pesticides.
-In the field of medicine, it can be used to synthesize a variety of biologically active compounds, such as anti-gout drugs, anti-cancer drugs and anti-inflammatory drugs.

Method:
- ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate can be obtained by reacting 2-trifluoromethylpyrimidine with ethyl chloroformate.
-The specific steps include using a base as a catalyst to react 2-trifluoromethylpyrimidine with ethyl chloroformate under appropriate reaction conditions to generate the target product.

Safety Information:
- ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate has no known serious hazards under normal use and storage conditions.
-But it is an organic compound that may be irritating and toxic to the human body, so you should follow appropriate safe operating procedures when using it.
-It is recommended to wear protective gloves, goggles and chemical protective clothing during the operation, and ensure that the operation is carried out in a well-ventilated area.

Please note that the above information is for reference only. If you need to apply the compound specifically, please operate under laboratory or professional guidance and follow relevant safety procedures.

Last Update：2024-04-09 20:49:11